EFFECT OF ULTRAVIOLET-LIGHT ON DISEASE CHARACTERISTICS OF NZB-W MICE

  • 1 January 1978
    • journal article
    • research article
    • Vol. 5  (2) , 125-128
Abstract
The development of antinuclear antibodies, proteinuria and cumulative mortality was studied in 4 groups of NZB/W mice [as a model for human systemic lupus erythematosus]. Two groups were exposed to different amounts of UV light (UVL) and 1 group was bred and raised in total darkness. The 4th group served as a control. No significant difference was noted between the groups in the development of antinuclear antibodies, proteinuria or in cumulative mortality. No major role of UVL as an environmental factor in the development of this disease was demonstrated.