Comparison of two different DMA-binding modes of the NF-κB p50 homodimer
- 1 March 1996
- journal article
- Published by Springer Nature in Nature Structural & Molecular Biology
- Vol. 3 (3) , 224-227
- https://doi.org/10.1038/nsb0396-224
Abstract
Analysis of the NF-kappa B p50 homodimer bound to different DNA sequences shows that the protein can recognize half-site spacings of either three or four base pairs. The protein can maintain most of its DNA contacts by a relative reorientation of its two domains.Keywords
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