Salmonella enterica Serovar Typhi Strains Isolated in Korea Containing a Multidrug Resistance Class 1 Integron
Open Access
- 1 June 2003
- journal article
- research article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 47 (6) , 2006-2008
- https://doi.org/10.1128/aac.47.6.2006-2008.2003
Abstract
Six strains of Salmonella enterica serovar Typhi which were resistant to ampicillin, chloramphenicol, trimethoprim-sulfamethoxazole, streptomycin, tetracycline, and gentamicin were isolated in Korea. This multidrug resistance was transferred by a conjugative plasmid of about 50 kb. The plasmid harbored a class 1 integron, which included six resistance genes, aacA4b , catB8 , aadA1 , dfrA1 , aac ( 6′ )- IIa , and the novel blaP2 , in that order. All of the isolates showed the same-size plasmids and the same ribotyping patterns, which suggests a clonal spread of these multidrug-resistant isolates.Keywords
This publication has 17 references indexed in Scilit:
- Antimicrobial drug resistance inSalmonella: problems and perspectives in food- and water-borne infectionsFEMS Microbiology Reviews, 2002
- Family of Class 1 Integrons Related to In4 from Tn 1696Antimicrobial Agents and Chemotherapy, 2001
- Characterisation of two new gene cassettes,aadA5anddfrA17FEMS Microbiology Letters, 2000
- Carbenicillin‐hydrolysing penicillinase mediated by a plasmid of Proteus mirabilis and its relationship to the PSE‐type enzymes of Pseudomonas aeruginosa Journal of Applied Microbiology, 1997
- Multidrug-Resistant Salmonella typhi: A Worldwide EpidemicClinical Infectious Diseases, 1997
- Gene cassettes: a new class of mobile elementMicrobiology, 1995
- Ribotyping as an epidemiologic tool forEscherichia coliEpidemiology and Infection, 1994
- A spontaneous point mutation i theaac(6′)-lb′gene results in altered substrate specificity of aminoglycoside 6′-N-acetyltransferase of aPseudomonas fluorescensstrainFEMS Microbiology Letters, 1994
- Isolation, characterization, and DNA sequence analysis of an AAC(6')-II gene from Pseudomonas aeruginosaAntimicrobial Agents and Chemotherapy, 1989
- The Use of Analytical Isoelectric Focusing for Detection and Identification of -LactamasesJournal of General Microbiology, 1975