Synthesis and Biological Evaluation of 5-Substituted Derivatives of the Potent Antiherpes Agent (north)-Methanocarbathymine
- 14 October 2003
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of Medicinal Chemistry
- Vol. 46 (23) , 5045-5054
- https://doi.org/10.1021/jm030241s
Abstract
No abstract availableKeywords
This publication has 36 references indexed in Scilit:
- Comparison of the genotoxic and apoptosis-inducing properties of ganciclovir and penciclovir in Chinese hamster ovary cells transfected with the thymidine kinase gene of herpes simplex virus-1: Implications for gene therapeutic approachesCancer Gene Therapy, 2000
- RNA Levels of Human Retrovirus Receptors Pit1 and Pit2 Do Not Correlate with Infectibility by Three Retroviral Vector PseudotypesHuman Gene Therapy, 1998
- “Suicide” gene for the control of graft-versus-host diseaseCurrent Opinion in Hematology, 1998
- (1S,2R)-[(Benzyloxy)methyl]cyclopent-3-enol. A Versatile Synthon for the Preparation of 4‘,1‘a-Methano- and 1‘,1‘a-Methanocarbocyclic NucleosidesThe Journal of Organic Chemistry, 1997
- A New Method for Quantitative Determination of Tritium-Labeled Nucleoside Kinase Products Adsorbed on DEAE-CelluloseBiochemical and Biophysical Research Communications, 1996
- Cytogenetic genotoxicity of antiherpes virostatics in Chinese hamster V79-E cells. I. Purine nucleoside analoguesAntiviral Research, 1996
- A Short High Yielding Synthesis of the Potent Anti-VZV Carbocyclic Nucleoside Analogue Carba-BVDUNucleosides and Nucleotides, 1995
- Acyclic Guanosine Analogs Inhibit DNA Polymerases .alpha., .delta., and .epsilon. with Very Different Potencies and Have Unique Mechanisms of ActionBiochemistry, 1995
- Synthesis and antiviral activity of the enantiomeric forms of carba-5-iodo-2'-deoxyuridine and carba-(E)-5-(2-bromovinyl)-2'-deoxyuridineJournal of Medicinal Chemistry, 1989
- Synthesis and Central Dopaminergic Effects of N-(4,6-Dimethyl-2-pyridinyl)benzamidesJournal of Medicinal Chemistry, 1985