Calcium channel modulation by β-adrenergic neurotransmitters in the heart
- 1 December 1987
- journal article
- review article
- Published by Springer Nature in Cellular and Molecular Life Sciences
- Vol. 43 (11-12) , 1173-1175
- https://doi.org/10.1007/bf01945518
Abstract
Calcium ions play a crucial role in the regulation of the heart beat. During each action potential Ca2+ ions flow into the cell and are directly and indirectly involved in generation of pacemaker potentials and of contractile force. Adrenergic and cholinergic neurotransmitters modulate Ca2+ influx. The most detailed analysis has been made on the mechanism of the β-adrenergic effect on calcium channels in cardiac cell membranes. This is briefly summarized in a personal account, while for more detailed information the reader is referred to more extensive recent reviews16, 22.Keywords
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