YLR209c Encodes Saccharomyces cerevisiae Purine Nucleoside Phosphorylase
Open Access
- 15 August 2001
- journal article
- research article
- Published by American Society for Microbiology in Journal of Bacteriology
- Vol. 183 (16) , 4910-4913
- https://doi.org/10.1128/jb.183.16.4910-4913.2001
Abstract
The yeast YLR209c ( PNP1 ) gene encodes a protein highly similar to purine nucleoside phosphorylases. This protein specifically metabolized inosine and guanosine. Disruption of PNP1 led to inosine and guanosine excretion in the medium, thus showing that PNP1 plays an important role in the metabolism of these purine nucleosides in vivo.Keywords
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