Snuff-dipping in College Students: A Clinical Profile

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Abstract
The snuff-dipping habits of 30 male young adult volunteers at an Eastern Military College were monitored by chemical analyses of the tobacco products and of the saliva for nicotine and nitrosamines. In addition, nicotine and its major metabolite cotinine were determined in saliva and in urine by radioimmunoassays. The snuff brands consumed by the students were high in carcinogenic tobacco-specific N-nitrosamines (5.4–66 μg/g). This was also reflected in the saliva analyses of snuff-dippers which revealed the presence of 0.1–0.76 μg of nitrosamines per gram of saliva. The higher urinary excretion of nicotine and cotinine with increasing years of snuff-use indicates nicotine habituation of the snuff-dippers. These findings give rise to concerns about an increased risk for oral cancer with prolonged use of oral snuff.

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