An Approach to the Antiinflammatory Activity of Borjatriol
- 26 February 1984
- journal article
- research article
- Published by Georg Thieme Verlag KG in Planta Medica
- Vol. 50 (01) , 90-92
- https://doi.org/10.1055/s-2007-969630
Abstract
The antiinflammatory activity of borjatriol (a diterpenoid isolated from Sideritis mugronensis Borja) was tested using the cotton pellet-granuloma assay. The compound inhibited the granuloma weight and the serum lysozyme activity in a dose-dependently way. The determination of this enzyme has allowed us to distinguish between an irritant (carrageenan) which reduces the granuloma weight and antiinflammatory substances (phenylbutazone and borjatriol).Keywords
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