A Molecular Model for the Interaction of Ethidium Bromide with Deoxyribonucleic Acid
- 1 October 1964
- journal article
- research article
- Published by Wiley in Berichte der Bunsengesellschaft für physikalische Chemie
- Vol. 68 (8-9) , 805-808
- https://doi.org/10.1002/bbpc.19640680830
Abstract
X‐ray diffraction and molecular model building studies have led to a model for the interaction between deoxyribonucleic acid (DNA) and ethidium bromide in which the planar ring system of the drug is intercalated between successive base‐pairs of the DNA. This model is compared with that proposed by Lerman for the DNA‐proflavine interaction.Keywords
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