METRONIDAZOLE IN BREAST-MILK

  • 1 January 1981
    • journal article
    • research article
    • Vol. 57  (1) , 48-50
Abstract
Metronidazole [M] breast milk concentrations were assayed in 3 women who were treated with a single 2.0-g dose for trichomoniasis [Trichomonas vaginalis infection]. Highest drug concentrations were found 2 and 4 h after administration and they declined over the next 12-24 h. Apparently if breast-feeding is withheld for 12-24 h after the dose, infants will be exposed to a greatly reduced amount of M. As M use in nursing mothers is currently not recommended, this may be the regimen of choice for trichomoniasis treatment in lactating women.

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