Dissection of the human brain as a method for its fractionation by weight

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Abstract
Twenty human brains were weighed as fresh specimens and for varying periods of time following fixation in 10% formol. Meninges and blood vessels were removed, the brain stem was trimmed uniformly and a final total cleaned brain weight was thereby obtained. Ten brains (group I) were specially dissected to determine the respective weights of eight brain subdivisions. Ten fixed brains (group II) were boiled for 20 minutes, then refixed in formol for 30 days. Group II specimens were then dissected into the same eight subdivisions.The use of standardized procedures and meticulous dissection yielded surprisingly uniform fractionation of the specimens in both groups I and II. This study indicates that precise gross dissection can be used as an accurate method of subdividing the human brain by weight.

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