Properties of Fibrin Dissolved in Urea Solutions.
- 1 January 1950
- journal article
- research article
- Published by Danish Chemical Society in Acta Chemica Scandinavica
- Vol. 4 (2) , 344-350
- https://doi.org/10.3891/acta.chem.scand.04-0344
Abstract
Fibrin clots are soluble in concentrated urea solns. When urea is dialyzed out at pH 6.5, an opaque coarse type gel results; at pH 8, a fine type gel is formed. At 30% urea concn. the viscosity of fibrin and fibrinogen solns. were similar from pH 6 to 12. At 20% concn. the viscosity rose at pH values more alkaline than 7.6 and reached a max. value at 8.6; it then decreased to the original value. At 15% or lower, the increase in viscosity led to gelation; at high pH the gel redissolved.This publication has 3 references indexed in Scilit:
- The Urea Denaturation of Fibrinogen. I. Kinetic Aspects.Acta Chemica Scandinavica, 1950
- THIOL‐VITAMIN K MECHANISM IN THE CLOTTING OF FIBRINOGENImmunology & Cell Biology, 1945
- A STUDY ON THE CONVERSION OF FIBRINOGEN TO FIBRINAmerican Journal of Physiology-Legacy Content, 1944