Statistical properties of the allelic and genotypic transmission/disequilibrium test for multiallelic markers

1 January 1995

journal article
research article
Published by Wiley in Genetic Epidemiology

Vol. 12 (6) , 865-870
https://doi.org/10.1002/gepi.1370120656

Abstract

The transmission/disequilibrium test (TDT) is extended in two ways for a multiallelic marker: (1) to compare transmitted and nontransmitted alleles from a single heterozygous parent and (2) to compare genotypes formed by the two transmitted alleles and genotypes formed by the two nontransmitted alleles using the information on both parents, heterozygous or not, simultaneously.

Keywords

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