HIGH-AND LOW-DOSE FENTANYL ANAESTHESIA: CIRCULATORY AND PLASMA CATECHOLAMINE RESPONSES DURING CHOLECYSTECTOMY

Abstract
The cardiovascular and neuroendocrine effects of a high-dose fentanyl anaesthesia (100 μg/kg body weight) were compared with those of a balanced type of fentanyl anaesthesia (5 μg kg−1) during upper abdominal surgery. High-dose fentanyl anaesthesia prevented the increase in catecholamine concentrations and attenuated the circulatory response to surgical stress seen in the group anaesthetized with the balanced technique of anaesthesia.