Abstract
The ingestion by albino rats of a diet containing 1% of orotic acid brought about not only fatty infiltration of the liver but also an increase in the total and the soluble protein. Adenine nullified both the fat and protein build-up. An investigation of the lipoprotein fraction showed that there was less in the livers of treated animals, but the percentage of fat in these lipoproteins was higher than that found in the control livers.