Mapping of the nadB Locus Adjacent to a Previously Undescribed Purine Locus in Escherichia coli K-12

Abstract
It is proposed that all mutants blocked in the de novo pathway of nicotinamide adenine dinucleotide biosynthesis be designated nad rather than nic . It is further suggested that mutants blocked in the pyridine nucleotide cycle be designated pnc . The nadB locus and a previously unidentified pur locus are cotransducible. These two loci have been mapped near minute 49 on the standard genetic map of Escherichia coli . The order of genes in that region is purC-guaB-purG-glyA-pur-nadB-tyrA-pheA .

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