Infant mortality from spina bifida, congenital hydrocephalus, monstrosity, and congenital diseases of the cardiovascular system in England and Wales
- 1 February 1971
- journal article
- Published by Wiley in Annals of Human Genetics
- Vol. 34 (3) , 295-305
- https://doi.org/10.1111/j.1469-1809.1971.tb00242.x
Abstract
SUMMARY: The epidemiology of congenital abnormalities is reviewed and the data available in the Registrar General's Annual Reviews for England and Wales from 1848 to 1967 are analysed statistically.The time and place of reported epidemics of spina bifida and anencephalus are tabulated.It is concluded that the pattern of epidemics of dysraphism in time and place is inconsistent with a viral aetiology, and it is suggested that a proportion of embryos may be genetically susceptible to an antimetabolite present in a food under certain conditions of preservation, preparation or storage.Keywords
This publication has 11 references indexed in Scilit:
- A Probable Epidemic of Congenital Hydrocephalus in 1940-1941Developmental Medicine and Child Neurology, 2008
- PATHOGENESIS OF SPINA BIFIDAThe Lancet, 1969
- Epidemiology of Stillbirths from Congenital Abnormalities in England and Wales, 1961–1966Developmental Medicine and Child Neurology, 1969
- THE RECENT DECLINE IN PREVALENCE OF ANENCEPHALY AND SPINA BIFIDA1American Journal of Epidemiology, 1969
- Viral Infection in Pregnancy and Congenital CNS Malformations in ManArchives of Neurology, 1969
- Anencephalus in Belfast and DublinIrish Journal of Medical Science, 1969
- GENETICS OF ANENCEPHALY AND SPINA BIFIDA ?The Lancet, 1968
- ANENCEPHALUS: A 23‐YEAR SURVEY IN A SYDNEY HOSPITALThe Medical Journal of Australia, 1967
- Causes of malformations of the heart.BMJ, 1965
- ON ESTIMATING THE RELATION BETWEEN BLOOD GROUP AND DISEASEAnnals of Human Genetics, 1955