Adherence of Mouse Macrophages to Plastic Lens Implants-Resulting in the Formation of a Cellular Membrane

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Abstract
An experiment for the study of the adherence of mouse macrophages to lens implants under tissue culture conditions has been developed. Formation of a continuous monolayer of cells on the surface of a plastic implant after 18 hours of incubation is demonstrated when this is exposed to a fluid with a high concentration of macrophages. Fewer macrophages in a thin fluid layer on the surface of a tissue culture dish made of clear plastic under the same conditions also showed adherence in a noncontinuous pattern. Some of these macrophages adherent to the surface of the plastic dish resembled reactive cell types that have previously been seen on lens implants removed from human eyes.

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