Enantiospecific synthesis of the C-17–C-20 and C-21–C-27 synthons of the antineoplastic macrolide bryostatins

Abstract
Synthons corresponding to the C-17–C-20 and C-21–C-27 fragments of the antineoplastic macrolide bryostatins have been synthesized starting from the readily available (R)-pantolactone and D-galactono-1,4-lactone respectively.

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