A Gas Chromatographic Screening Procedure for Acid and Neutral Drugs in Blood
- 1 May 1979
- journal article
- research article
- Published by Oxford University Press (OUP) in Journal of Analytical Toxicology
- Vol. 3 (3) , 87-91
- https://doi.org/10.1093/jat/3.3.87
Abstract
A relatively simple extraction procedure for the comprehensive screening of acid, neutral, and many basic drugs is described. The procedure involves a single extraction into toluene-ether, evaporation, and combined dissolution and clean-up of the residue using ethanol and hexane. The ethanol phase is used for analysis by gas chromatography using a flame-ionization detector. More than 80 components have been detected and identified in blood by the procedure. The procedure can be used as a routine screen in clinical toxicology cases with results available within two hours.This publication has 1 reference indexed in Scilit:
- A Rapid, Comprehensive Screening Procedure for Basic Drugs in Blood or Tissues by Gas ChromatographyJournal of Analytical Toxicology, 1978