Comparison of Growth Responses of 2-Day-Old Pigs to Streptomycin, Aureomycin, and Crude APF, Alone and in Combination with B12

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Abstract
A “semisynthetic milk” (low B12) using vitamin-free casein as a source of protein was fed to 2-day-old pigs to demonstrate the growth-stimulating effects of B12, streptomycin, aureomycin, and crude APF. A dietary requirement for B12 for the baby pig was suggested. Supplementation with aureomycin alone, aureomycin plus B12, streptomycin plus B12, and a combination of aureomycin, streptomycin, and B12 increased the daily rate of gain over that of the control ration. No growth-promoting effect resulted from the supplementation of streptomycin alone or crude APF to the basal ration. Better growth was observed when streptomycin and B12 were fed together than when streptomycin was fed alone. This was not apparent with aureomycin. No consistent differences in the hemoglobin levels were apparent between the various lots.