Uptake of Adenosine by Cultured Cerebral Vascular Smooth Muscle Cells
- 1 April 1983
- journal article
- research article
- Published by Wiley in Journal of Neurochemistry
- Vol. 41 (4) , 939-941
- https://doi.org/10.1111/j.1471-4159.1983.tb09037.x
Abstract
Adenosine uptake by cerebral smooth muscle cells is a carrier-mediated process. The Km value for adenosine uptake is 10.0 μM and the Vmax is 0.95 nmol/ min-mg cell protein. This uptake system is inhibited by the adenosine analog 2-chloroadenosine at low adenosine concentrations. These results prove the existence of a nucleoside transport system associated with cerebral smooth muscle.Keywords
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