The novel NK1 receptor antagonist MK–0869 (L–754,030) and its water soluble phosphoryl prodrug, L–758,298, inhibit acute and delayed cisplatin-induced emesis in ferrets

This publication has 35 references indexed in Scilit:

• The site of the anti-emetic action of tachykinin NK1 receptor antagonists may exist in the medullary area adjacent to the semicompact part of the nucleus ambiguus
  Brain Research, 1999
• The tachykinin NK1 receptor antagonist GR205171 abolishes the retching activity of neurons comprising the central pattern generator for vomiting in dogs
  Neuroscience Research, 1999
• GR205171: A novel antagonist with high affinity for the tachykinin NK1 receptor, and potent broad-spectrum anti-emetic activity
  Regulatory Peptides, 1996
• The pharmacology of the emetic response to upper gastrointestinal tract stimulation in Suncus murinus
  European Journal of Pharmacology, 1996
• Broad spectrum antiemetic effects of CP-122,721, a tachykinin NK1 receptor antagonist, in ferrets
  European Journal of Pharmacology, 1996
• The pharmacology of GR203040, a novel, potent and selective non‐peptide tachykinin NK₁ receptor antagonist
  British Journal of Pharmacology, 1995
• The broad‐spectrum anti‐emetic activity of the novel non‐peptide tachykinin NK₁ receptor antagonist GR203040
  British Journal of Pharmacology, 1995
• Anti-emetic profile of a non-peptide neurokinin NK1 receptor antagonist, CP-99,994, in ferrets
  European Journal of Pharmacology, 1993
• Ondansetron Compared with High-Dose Metoclopramide in Prophylaxis of Acute and Delayed Cisplatin-Induced Nausea and Vomiting
  Annals of Internal Medicine, 1990
• Pharmacological properties of GR38032F, a novel antagonist at 5‐HT₃ receptors
  British Journal of Pharmacology, 1988