Hormonal Treatment of Cryptorchidism

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Abstract
To the Editor: In their article in the February 20 issue, Rajfer et al. conclude that hormonal treatment is in most cases ineffective in promoting testicular descent.1 In addition, they claim that the success rate of over 50 percent achieved by treatment of cryptorchidism with gonadotropin-releasing hormone (GnRH) in European and Australian studies can be explained by the inclusion of large numbers of boys with retractile testes. Physical examination has been shown to be unreliable in detecting retractile testes.2 The ultimate criterion for differentiating retractile from truly cryptorchid testes is the histologic appearance of testicular biopsy specimens.2 A randomized study . . .