A NOVEL PROCEDURE FOR THE PREPARATION OF 1-OH SUGAR DERIVATIVES USING 2-METHOXYETHYL GLYCOSIDES

Abstract
Treatment of benzyl-protected 2-methoxyethyl glycopyranosides with titanium tetrachloride followed by hydrolysis provides a new method for the preparation of the corresponding 1-OH sugar derivatives. The present method is shown to be useful for the preparation of mono-O-acetyl- and mono-O-allyl-tri-O-benzyl-d-glucopyranoses.