ReductiveN-Monoalkylation of Primary Aromatic Amines
- 1 January 1993
- journal article
- research article
- Published by Georg Thieme Verlag KG in Synthesis
- Vol. 1993 (01) , 121-125
- https://doi.org/10.1055/s-1993-25813
Abstract
Primary aromatic amines 1 with a variety of ring substituents are easily converted to their N-monoalkyl derivatives 3 by a simple variation of the sodium borohydride/sulfuric acid/carbonyl compound procedure previously described for their N-permethylations. The procedure is suitable for the α-monodeuterium labelling of the new N-substituent.Keywords
This publication has 0 references indexed in Scilit: