DIURNAL CHANGES IN THE LIVER DURING PREGNANCY

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Abstract
It has been shown that curves of the changes in the wt., water and glycogen content of the liver are bimodal. In this study the livers of white rats at the 8th-10th day of pregnancy and at term were examined and water and glycogen evaluated at 2-hr. intervals for 24 hrs. following a single 2-hr. feeding period. The change in the amts. of these constituents from the pre-feeding level, detd. every 2. hrs.'' indicates that even in pregnant animals, wherein demands on the maternal liver may be greater, the curves of the changes in liver wts., water and glycogen, following a single feeding, are bimodal. The peaks occur somewhat earlier, and amts. of glycogen recovered are less, in pregnant than in normal animals. Amts. of water in maternal livers were greater during early pregnancy than at term.

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