Suppression of the Hypercalcemia of Thyrotoxicosis by Corticosteroids

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Abstract
WITHIN the last decade the problem of hypercalcemia has received much emphasis for several reasons. It is now realized that hypercalcemic symptoms may mimic disease of the musculoskeletal, gastrointestinal, urinary and neuropsychiatric systems.1 Furthermore, the causes of hypercalcemia other than hyperparathyroidism are many and include thyrotoxicosis, neoplasm without metastasis, acute osteoporosis, the milk-alkali syndrome and adrenal insufficiency.1 , 2 Unfortunately, there is no single test or procedure that will differentiate the multiple causes, and the diagnosis is often one of exclusion.1 2 3 Osteoporosis and increased fecal and urinary calcium excretion in hyperthyroidism have been recognized for more than fifty years. Although hypercalcemia occurring . . .

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