Understanding carbohydrate-carbohydrate Interactions by means of glyconanotechnology
- 1 January 2004
- journal article
- review article
- Published by Springer Nature in Glycoconjugate Journal
- Vol. 21 (3/4) , 149-163
- https://doi.org/10.1023/b:glyc.0000044846.80014.cb
Abstract
Carbohydrate-carbohydrate interaction is a reliable and versatile mechanism for cell adhesion and recognition. Glycosphingolipid (GSL) clusters at the cell membrane are mainly involved in this interaction. To investigate carbohydrate-carbohydrate interaction an integrated strategy (Glyconanotechnology) was developed. This strategy includes polyvalent tools (gold glyconanoparticles) mimicking GSL clustering at the cell membrane as well as analytical techniques such as AFM, TEM, and SPR to evaluate the interactions. The results obtained by means of this strategy and current status are presented. Published in 2004.Keywords
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