3-Nitropropanal and 3-Nitropropanol: Preparation of the Parent Compounds and Derivatives

Abstract
3-Nitropropanal has been prepared for the first time by 1,4-nitrite addition to acrolein. Several acetals of 3-nitropropanal are described, as well as 3-nitropropanal and some of its ethers. 3-Nitropropanal has been obtained by borane-dimethyl sulfide reduction of both 3-nitropropanal and 3-nitropropanoic acid. These reactions make available a variety of nitro compounds known as, or expected to become, highly useful and versatile building blocks for organic syntheses.

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