Genotoxic effects of some systemic pesticides: In vivo chromosomal aberrations in bone marrow cells in rats

1 January 1988

journal article
research article
Published by Wiley in Environmental Mutagenesis

Vol. 12 (2) , 235-242
https://doi.org/10.1002/em.2860120209

Abstract

The genotoxic effects of five pesticides (benomyl, 2,4-D, dimecron, monocrotophos, and vitavax) were evaluated in the rat bone marrow cytogenetic assay. The spectrum of aberrations observed included chromatid breaks, chromatid fragments, ring chromosomes, dicentric chromosomes, and chromosome fragments. It was observed that 2,4-D, dimecron, and vitavax were clastogenic, but the results obtained with benomyl and monocrotophos were equivocal.

Keywords

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