Template‐free ribosomal synthesis of polypeptides from aminoacyl‐tRNA
- 29 September 1986
- journal article
- Published by Wiley in FEBS Letters
- Vol. 206 (1) , 142-146
- https://doi.org/10.1016/0014-5793(86)81356-4
Abstract
Misacylated phenylalanyl-tRNALys, just as lysyl-tRNALys, but not phenylalanyl-tRNAPhe, have been shown to serve as substrates for ribosomal synthesis of polypeptides (polyphenylalanine and polylysine, respectively) in the absence of a template polynucleotide (poly(A)). The conclusion was made that it is the structure of tRNA that determines the ability of the aminoacyl-tRNALys to participate in peptide elongation on ribosomes without codon-anticodon interactions.Keywords
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