Pregnancy: Fetal and maternal morbidity and mortality in menopausal women aged 45–63 years

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Abstract
The pregnancies achieved up to April 1994 among 162 recipients who participated in our oocyte donation programme were studied. Of these, 113 were >45 years old and 49 were <45 years old (25–44); ∼300 women were not admitted to our programme for various reasons. The 113 recipients considered in this study were divided into two age groups: group A, 45–49 years old (54 patient cycles); and group B, 50–60 years old (58 patient cycles); there was also one case of a 63 year old woman. Overall, 44 clinical pregnancies were established in 113 recipient cycles (38.9%) and 44 healthy babies have been delivered; 10 babies were lost (eight miscarriages, one abruptio placentae and one severe gestational proteinuria hypertension at 25 weeks). There was also one case of medium hypertension (at 32 weeks) and four cases of mild hypertension (30, 32, 33 and 35 weeks). There were no cases of maternal diabetes among the pregnant women due to the strict selection criteria. There were no maternal deaths associated with these pregnancies. Regarding neonatal morbidity and mortality, there was one premature labour in the 31st week in a 53 year old woman because of an accidental fall in an airport, and another one in a 51 year old woman in the 25th week. The remaining babies had good Apgar scores and good weights. There were no child deaths and to date there have been no reports of fetal malformation. All babies delivered are in good health. The pregnancy in the 63 year old woman is still ongoing and has reached the 31st week without any problems; an echograph indicates a healthy fetus that has reached 1.6 kg.

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