Consumption Coagulopathy in Septicemic Shock
- 17 October 1968
- journal article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 279 (16) , 884-885
- https://doi.org/10.1056/nejm196810172791610
Abstract
Disseminated intravascular coagulation is now recognized as responsible for most of the acutely acquired hypofibrinogenemic disorders that may be found associated with a variety of obstetric syndromes, promyelocytic leukemia, purpura fulminans, carcinomatosis, shock, fat embolism and septicemia. The characteristic clotting profile includes decreased levels of fibrinogen, platelets and Factors II, V and VIII because of the direct action of thrombin. In addition, fibrinogen or fibrin split products, resulting from secondary activation of the fibrinolytic system, are usually detected. The paper by Corrigan, Ray and May in this issue of the Journal emphasizes the frequency in which this syndrome occurs in . . .Keywords
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