Pathogenicity of Highly Pathogenic Avian Influenza Virus (H5N1) in Adult Mute Swans
Open Access
- 1 August 2008
- journal article
- Published by Centers for Disease Control and Prevention (CDC) in Emerging Infectious Diseases
- Vol. 14 (8) , 1267-1270
- https://doi.org/10.3201/eid1408.080078
Abstract
Adult, healthy mute swans were experimentally infected with highly pathogenic avian influenza virus A/Cygnus cygnus/Germany/R65/2006 subtype H5N1. Immunologically naive birds died, whereas animals with preexisting, naturally acquired avian influenza virus–specific antibodies became infected asymptomatically and shed virus. Adult mute swans are highly susceptible, excrete virus, and can be clinically protected by preexposure immunity.Keywords
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