Phosphoinositide-specific Inositol Polyphosphate 5-Phosphatase IV Inhibits Akt/Protein Kinase B Phosphorylation and Leads to Apoptotic Cell Death
Open Access
- 1 February 2002
- journal article
- research article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 277 (8) , 6266-6272
- https://doi.org/10.1074/jbc.m105969200
Abstract
No abstract availableKeywords
This publication has 41 references indexed in Scilit:
- Overexpression of SH2-Containing Inositol Phosphatase 2 Results in Negative Regulation of Insulin-Induced Metabolic Actions in 3T3-L1 Adipocytes via Its 5′-Phosphatase Catalytic ActivityMolecular and Cellular Biology, 2001
- Phosphatidylinositol 4-Phosphate 5-Kinase Type I Is Regulated through Phosphorylation Response by Extracellular StimuliPublished by Elsevier ,2001
- The PI3K‒PDK1 connection: more than just a road to PKBBiochemical Journal, 2000
- A Dual Role for Src Homology 2 Domain–Containing Inositol-5-Phosphatase (Ship) in ImmunityThe Journal of Experimental Medicine, 2000
- FcγRIIb Modulation of Surface Immunoglobulin-induced Akt Activation in Murine B CellsPublished by Elsevier ,1999
- Role of phosphatidylinositol 3,4,5-trisphosphate in regulating the activity and localization of 3-phosphoinositide-dependent protein kinase-1Biochemical Journal, 1999
- Negative Regulation of PKB/Akt-Dependent Cell Survival by the Tumor Suppressor PTENCell, 1998
- Mitogenic Activation, Phosphorylation, and Nuclear Translocation of Protein Kinase BβJournal of Biological Chemistry, 1997
- Phosphatidylinositol-4-phosphate 5-Kinase Isozymes Catalyze the Synthesis of 3-Phosphate-containing Phosphatidylinositol Signaling MoleculesPublished by Elsevier ,1997
- Direct Regulation of the Akt Proto-Oncogene Product by Phosphatidylinositol-3,4-bisphosphateScience, 1997