Effect of Barbituric Acid on Alloxan Diabetes in Rats and Dogs
- 1 August 1955
- journal article
- research article
- Published by American Physiological Society in American Journal of Physiology-Legacy Content
- Vol. 182 (2) , 267-268
- https://doi.org/10.1152/ajplegacy.1955.182.2.267
Abstract
The diabetogenic effect of alloxan injected intravenously in rats and dogs before and after the administration of barbituric acid was studied. It was found that pre-treatment with barbituric acid injected either intravenously or intraperitoneally counteracted the diabetogenic effect of alloxan. However barbituric acid did not prevent diabetes when given after the injection of alloxan.Keywords
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