Colorimetric Topography of Atherosclerotic Lesions by Television Image Processing

Abstract
A measurement technique has been developed to quantify the degree and location of sudanophilic lesions in necropsy specimens. Transparencies of longitudinally opened arterial specimens are digitized by television image processing to discrete values of location and luminance. The image is photographically partitioned to increase location information. Binary maps are produced by thresholding the image at several luminance levels of a preprocessed hue. Thus, only the preprocessed hue is available for luminance thresholding. By means of a standard transformation to suppress biological variation, the binary maps of numerous specimen images are overlaid to produce statistical contour maps whose topography represents the level of Sudan IV strain saturation. The accuracy and precision of this technique are far superior to previous methods.

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