Late relapse from complete remission in nodular and diffuse histiocytic lymphoma
- 15 October 1983
- Vol. 52 (8) , 1356-1359
- https://doi.org/10.1002/1097-0142(19831015)52:8<1356::aid-cncr2820520803>3.0.co;2-m
Abstract
Twelve patients with unfavorable prognosis lymphomas (diffuse histiocytic lymphoma, 11; nodular histiocytic lymphoma, 1) treated predominantly with radiation therapy, are described in whom relapse of disease occurred late (>2.5 years, 2.8–26 years; median, 6.25 years) after achieving a complete remission. Although relapse probably represented regrowth of clinically quiescent tumor, it is also possible that these were second malignancies, perhaps occurring in a predisposed host. Continued long-term analysis of clinical trials is important to document this uncommon occurrence.This publication has 10 references indexed in Scilit:
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