Studies on .BETA.-lactam antibiotics. VI. Effect on antibacterial activity of .ALPHA.-substituents in the 2-(2-amino-4-thiazolyl)acetyl side chain of a cephalosporin nucleus.

Abstract
Synthesis and in vitro antibacterial [gram negative bacteria, enterobacteria, Staphylococcus aureus] activity of semisynthetic cephalosporins having an .alpha.-substituted 2-(2-amino-4-thiazolyl)acetyl side chain at the 7-position were described.