Antiplatelet Therapy

Publisher Website
Google Scholar
Abstract
(Second of Two Parts)Clinical Uses of Antiplatelet DrugsThe possibility that antiplatelet drugs may be useful in the prophylaxis or therapy of platelet-induced thromboembolism in man has aroused considerable interest in recent years. In addition, these drugs could also be useful in modifying other platelet-mediated pathologic processes (Table 1). In general, the use of these drugs assumes that platelet activation (e.g., adhesion, aggregation, secretion or thrombus formation) plays an important part in initiating or perpetuating an acute clinical event or pathologic process. In most cases the mechanism by which platelets contribute to these various processes is poorly understood. The . . .