Evolution favors protein mutational robustness in sufficiently large populations
Open Access
- 17 July 2007
- journal article
- Published by Springer Nature in BMC Biology
- Vol. 5  (1) , 29
- https://doi.org/10.1186/1741-7007-5-29
Abstract
An important question is whether evolution favors properties such as mutational robustness or evolvability that do not directly benefit any individual, but can influence the course of future evolution. Functionally similar proteins can differ substantially in their robustness to mutations and capacity to evolve new functions, but it has remained unclear whether any of these differences might be due to evolutionary selection for these properties.Keywords
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