Antabus and the metabolism of alcohol.

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  • 1 August 1950
    • journal article
    • Vol. 73  (2) , 137-40
Abstract
Antabus does not alter the rate of alcohol metabolism in dogs. It interferes with the metabolism of acetaldehyde, so that the ordinarily prompt removal of this substance from the tissues as it is produced in the metabolism of alcohol does not take place. It seems reasonable to assume that it is this accumulation of acetaldehyde in the tissues in abnormally high concentrations that is responsible for the unpleasant symptoms following the taking of alcohol by a patient receiving antabus.

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