Left Ventricular Mass in Patients With Type 2 Diabetes Is Independently Associated With Central but not Peripheral Pulse Pressure

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Abstract
The study population comprised 90 type 2 diabetic patients with normal ejection fractions (>50%), no history of coronary artery disease, and normal exercise stress echocardiograms. Patients underwent a standard echocardiographic assessment in which LVM was calculated by Devereux’s formula (5) and indexed to height2.7 (g/m2.7; LVM index [LVMI]). Resting supine brachial blood pressures were recorded in duplicate by sphygmomanometry. Central (ascending aortic) blood pressure and total arterial compliance were recorded by simultaneous radial tonometry and echocardiographic pulsed-wave Doppler as previously described (6). Brachial artery reactivity and carotid intima media thickness were obtained by standard ultrasound methods as previously described (7).