Gabapentin in orthostatic tremor: Results of a double-blind crossover with placebo in four patients
- 1 September 1998
- journal article
- case report
- Published by Wolters Kluwer Health in Neurology
- Vol. 51 (3) , 880-882
- https://doi.org/10.1212/wnl.51.3.880
Abstract
We treated four patients affected by orthostatic tremor (OT) with gabapentin in increasing doses (300 to 2,400 mg/d). OT was evaluated with patients' self-monitoring scales, tremor rating scales, electromyography(EMG) showing the 14- to 18-Hz frequencies, and EMG frequency analysis. All patients had transitory responses to clonazepam. Gabapentin induced disappearance of OT in three patients and consistent reduction in one. Crossover to placebo induced reappearance of tremor.Keywords
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