The abc's (and xyz's) of peptide sequencing
Top Cited Papers
- 1 September 2004
- journal article
- review article
- Published by Springer Nature in Nature Reviews Molecular Cell Biology
- Vol. 5 (9) , 699-711
- https://doi.org/10.1038/nrm1468
Abstract
Proteomics is an increasingly powerful and indispensable technology in molecular cell biology. It can be used to identify the components of small protein complexes and large organelles, to determine post-translational modifications and in sophisticated functional screens. The key - but little understood - technology in mass-spectrometry-based proteomics is peptide sequencing, which we describe and review here in an easily accessible format.Keywords
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