The Discriminatory Ability of Gastric Acid Secretion Tests in the Diagnosis of Recurrence after Truncal Vagotomy and Drainage for Duodenal Ulcer

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Abstract
Kronborg, O. The discriminatory ability of gastric acid secretion tests in the diagnosis of recurrence after truncal vagotomy and drainage for duodenal ulcer. Scand. J. Gastroent. 1973, 8, 483-489. The value of insulin and augmented histamine tests in predicting recurrence after vagotomy and drainage for duodenal ulcer was assessed in a series of 500 consecutively operated patients. Different criteria of recurrence were established by a discriminative analysis of gastric acid secretion parameters. Recurrence was predicted with a probability of about 50 per cent in patients with dyspepsia, the proportion between recurrences and dyspeptic non-recurrences being 1 : 3. The discriminatory ability of the insulin test was not better than that of the pre- and post-operative histamine test; also the time of performing the post-operative insulin test was of minor importance for the prediction of recurrence.