A possible relation between human pathogenicity of smallpox vaccines and virus growth at elevated temperatures
- 1 August 1974
- journal article
- research article
- Published by Cambridge University Press (CUP) in Epidemiology and Infection
- Vol. 73 (1) , 35-38
- https://doi.org/10.1017/s0022172400023809
Abstract
SUMMARY Seven smallpox vaccines of known human pathogenicity were tested for their ability to produce pocks on the chick chorioallantois at 39·7° C. Significant differences were found and the more pathogenic strains produced pocks with greater efficiency at 39·7° C. than did strains of average or low pathogenicity.Keywords
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