Michigan Molecular Interactions (MiMI): putting the jigsaw puzzle together
Open Access
- 27 November 2006
- journal article
- research article
- Published by Oxford University Press (OUP) in Nucleic Acids Research
- Vol. 35 (Database) , D566-D571
- https://doi.org/10.1093/nar/gkl859
Abstract
Protein interaction data exists in a number of repositories. Each repository has its own data format, molecule identifier and supplementary information. Michigan Molecular Interactions (MiMI) assists scientists searching through this overwhelming amount of protein interaction data. MiMI gathers data from well-known protein interaction databases and deep-merges the information. Utilizing an identity function, molecules that may have different identifiers but represent the same real-world object are merged. Thus, MiMI allows the users to retrieve information from many different databases at once, highlighting complementary and contradictory information. To help scientists judge the usefulness of a piece of data, MiMI tracks the provenance of all data. Finally, a simple yet powerful user interface aids users in their queries, and frees them from the onerous task of knowing the data format or learning a query language. MiMI allows scientists to query all data, whether corroborative or contradictory, and specify which sources to utilize. MiMI is part of the National Center for Integrative Biomedical Informatics (NCIBI) and is publicly available at: Author Webpage.Keywords
This publication has 18 references indexed in Scilit:
- BioGRID: a general repository for interaction datasetsNucleic Acids Research, 2006
- OrthoMCL-DB: querying a comprehensive multi-species collection of ortholog groupsNucleic Acids Research, 2006
- BIOZON: a hub of heterogeneous biological dataNucleic Acids Research, 2006
- Pfam: clans, web tools and servicesNucleic Acids Research, 2006
- A Human Protein-Protein Interaction Network: A Resource for Annotating the ProteomePublished by Elsevier ,2005
- miBLAST: scalable evaluation of a batch of nucleotide sequence queries with BLASTNucleic Acids Research, 2005
- InterPro, progress and status in 2005Nucleic Acids Research, 2004
- Reactome: a knowledgebase of biological pathwaysNucleic Acids Research, 2004
- Organelle DB: a cross-species database of protein localization and functionNucleic Acids Research, 2004
- Evidence for dynamically organized modularity in the yeast protein–protein interaction networkNature, 2004