Propranolol in the treatment of rage and violent behavior in patients with chronic brain syndromes

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Abstract
Four patients who had irreversible CNS lesions and socially disabling aggressiveness and outbursts of rage, which were not affected by high doses of major tranquilizers or anticonvulsants, were successfully treated with 320-520 mg/day of propranolol. Disorientation, memory impairment and psychotic thought processes associated with the CNS lesions were not altered by the propranolol.

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